VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide) 5mg is a 28-amino-acid neuropeptide supplied as a high-purity lyophilised powder for laboratory research use. Also known as Vasoactive Intestinal Polypeptide or PHM-27, VIP is one of the most widely studied peptides in immune, neurological and gastrointestinal research models. Every batch is third-party tested to >99% purity and dispatched from Australian stock.

What is VIP peptide?

Vasoactive Intestinal Peptide belongs to the glucagon/secretin peptide superfamily. In research settings it binds three G-protein-coupled receptors — VPAC1, VPAC2 and PAC1 — activating the adenylate cyclase pathway and raising intracellular cAMP. This mechanism underpins its interest across studies of vasodilation, smooth-muscle relaxation, immune modulation and circadian-rhythm regulation.

Research applications

• Anti-inflammatory research — studied for its modulation of pro- and anti-inflammatory cytokines in inflammatory disease models
• Neuroprotective research — investigated for neuronal survival and blood-brain barrier integrity
• Immune modulation — examined for its role balancing immune-cell activity and maintaining immune homeostasis
• Gastrointestinal studies — researched for gut motility, barrier function and smooth-muscle relaxation
• Circadian-rhythm studies — explored for its role in the suprachiasmatic nucleus (SCN) and biological-clock signalling

Product specifications

• Peptide: Vasoactive Intestinal Peptide (VIP / PHM-27)
• Quantity: 5mg per vial
• Form: Lyophilised (freeze-dried) white powder
• Purity: >99%, third-party (HPLC) tested
• Molecular formula: C147H237N43O43S
• Molecular weight: 3326.8 g/mol
• Sequence length: 28 amino acids

Reconstitution & storage

Reconstitute with bacteriostatic or sterile water prior to research use. Store lyophilised vials refrigerated at 4°C for up to 3 months, or frozen for up to 12 months. Once reconstituted, keep at 4°C and use within 30 days. Need to calculate your dilution? Use our peptide reconstitution calculator. You'll also need bacteriostatic water to reconstitute this peptide.

For laboratory research use only. Not for human or veterinary use, consumption, or therapeutic application. Not a drug, food, cosmetic, or dietary supplement. Handling restricted to qualified researchers in an appropriate setting.