Selank

Selank (10mg) — Tuftsin Analogue Anxiolytic Research Peptide

Selank (10mg) is supplied in Australia by Omega Peptides Australia from domestic stock, with same-day dispatch on orders placed before 12pm and an independent certificate of analysis for every batch. Commonly written as selank peptide, TP-7 or tuftsin analogue, it is a synthetic tuftsin analogue studied for anxiolytic activity and GABAergic modulation. The current batch (#199776) was tested by Janoshik Analytical on 9 July 2026 at 99.34% purity by HPLC.

Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Its sequence, Thr-Lys-Pro-Arg-Pro-Gly-Pro, is built from tuftsin, a naturally occurring tetrapeptide (Thr-Lys-Pro-Arg) released from the Fc region of immunoglobulin G that stimulates phagocytosis in immune cells, extended with the same Pro-Gly-Pro tail found in Semax. The tail was added to slow enzymatic breakdown and give the peptide a longer window of activity than tuftsin itself. Selank is also known by its development code TP-7, is described in the literature as a tuftsin analogue, and is written as selank peptide, Selank 10mg or by its one-letter sequence TKPRPGP.

Selank is studied in three main directions: anxiety and stress responses, learning and memory, and immune modulation inherited from its tuftsin origin. At the pathway level it alters the expression of genes involved in GABAergic neurotransmission, inhibits the enzymes that degrade enkephalins, increases hippocampal BDNF and changes serotonin metabolism, which is why it is described as a modulator of several systems rather than a ligand for one receptor.

Omega Peptides Australia supplies Selank as a high-purity (≥99% HPLC) COA-verified lyophilised powder in a sealed 10mg vial. Orders placed before 12pm are dispatched the same day from within Australia, and the batch Certificate of Analysis for every lot is published in our COA library.

Key research areas

• Anxiety and stress responses Selank has been examined in rodent models of anxiety, including elevated plus-maze and open-field paradigms, where anxiolytic-like behaviour has been reported without the sedation or motor impairment associated with benzodiazepines. Comparisons with classical anxiolytics are a recurring feature of this literature.
• GABAergic neurotransmission Gene-expression studies in rodent brain show that Selank alters the transcription of genes involved in GABAergic signalling, including GABA-A receptor subunits. This is the leading explanation for its anxiolytic-like profile and for reports that it modifies the response to GABA-acting compounds.
• Enkephalin degradation In vitro, Selank inhibits enkephalin-degrading enzymes in human serum. Because enkephalins dampen stress and pain signalling, prolonging their activity is proposed as a second mechanism for the behavioural findings, and it is a property Selank shares with Semax.
• Learning and memory Rodent studies have examined acquisition and retention in conditioned-response and maze tasks, with attention to memory consolidation under stress. Increased hippocampal BDNF expression is the mechanism most often cited for these findings.
• Immune modulation Tuftsin is an immunomodulatory peptide, and Selank retains that heritage. Research has looked at its effect on interleukin-6 expression and the balance of T helper cell cytokines, making it a compound of interest at the intersection of stress and immune function.
• Serotonin and monoamines Selank has been reported to influence serotonin metabolism in several brain regions and to alter the balance of monoamine neurotransmitters, linking it to research on mood-related behaviour.

Selank in Australia

Selank is not registered on the Australian Register of Therapeutic Goods, so it is not stocked by Chemist Warehouse, Priceline or other pharmacies. In Australia it is supplied as a research-grade lyophilised vial by domestic research suppliers. Omega Peptides Australia holds Selank in stock within Australia and dispatches orders placed before 12pm the same business day on tracked domestic delivery, so material arrives in days rather than waiting on an international shipment and customs. Every batch is tested independently and its certificate is published in the COA library before the vial ships. Browse the full range of research peptides in Australia on our homepage.

Selank is stocked in Australia as a 10mg vial alongside its acetylated form N-Acetyl Selank. It is most often paired with Semax, and the two are available together as the Semax + Selank bundle.

How Selank works

Selank does not bind a single well-defined receptor. Its anxiolytic-like activity in animal models is attributed mainly to changes in GABAergic transmission: the peptide alters the expression of genes encoding GABA-A receptor subunits and related proteins in the brain, and it has been proposed to modulate GABA-A receptor function in a way that complements, rather than duplicates, the action of benzodiazepines. In parallel it inhibits enkephalin-degrading enzymes, which prolongs the activity of endogenous enkephalins involved in stress and pain regulation, increases BDNF expression in the hippocampus and shifts serotonin metabolism. The tuftsin core also gives Selank immunomodulatory properties, including effects on interleukin-6 expression and T helper cytokine balance.

Pharmacokinetically, tuftsin itself is broken down within minutes. The Pro-Gly-Pro tail of Selank slows that degradation and extends the period of activity, although the intact peptide still has a short plasma half-life and is trimmed enzymatically from the N-terminus over time. This is the point of difference with N-Acetyl Selank, where an acetyl cap on the terminal threonine blocks aminopeptidase cleavage. Compared with Semax, which is derived from ACTH(4-10) and is studied for attention and neuroprotection, Selank is the tuftsin-derived member of the pair and is studied chiefly for anxiety, stress and immune endpoints.

Specifications

Available sizes and pricing

Selank is supplied in a single 10mg vial. For projects that pair it with Semax, the Semax and Selank Bundle combines both peptides with bacteriostatic water, syringes and swabs at a lower combined cost than buying each item on its own.

• 10mg vial — $79.99 (about $8.00 per mg)

Multi-vial pricing (10mg): 2 vials $143.98 (10% off, $71.99 each), 3 vials $209.97 (12.5% off, $69.99 each), 4 vials $271.97 (15% off, $67.99 each). The discount is applied automatically in the cart.

Quality and COA verification

Every batch of Selank is tested independently by Janoshik Analytical. HPLC is used to quantify purity and mass spectrometry to confirm that the measured molecular mass matches the expected value for the Thr-Lys-Pro-Arg-Pro-Gly-Pro sequence, so identity and purity are verified separately. A Certificate of Analysis is issued for each batch and published in our COA library, which means the lot number on a vial can be matched to its own report before the vial is opened. The peptide is supplied as a lyophilised powder in a sealed sterile vial, a format that protects it from hydrolysis during storage and transit, and every order is packed with protective cushioning for domestic delivery within Australia.

Frequently bought together

• Bacteriostatic Water (10mL) — $29.99, the recommended diluent for reconstituting lyophilised Selank
• Semax (10mg) — $79.99, the ACTH-derived companion peptide studied alongside Selank in cognition and stress models
• N-Acetyl Selank (10mg) — $129.99, the acetylated analogue for stability comparison work
• Semax and Selank Bundle — $169.99, both peptides with lab supplies in one kit

Research guides

• Semax Australia research guide
• Peptide storage guide: how to store lyophilised peptides properly
• COA testing explained for research peptides
• Peptide reconstitution calculator

Frequently asked questions

What is Selank?
Selank is a synthetic seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from tuftsin, a natural immune-regulating fragment of immunoglobulin G, with a Pro-Gly-Pro tail added for stability. It was developed at the Institute of Molecular Genetics in Moscow and is studied as an anxiolytic and nootropic research compound in models of stress, memory and immune function. Omega Peptides Australia supplies it as a lyophilised 10mg research vial for in-vitro laboratory use only.

What is Selank also known as?
It is most often written simply as Selank, but also appears as selank peptide, Selank 10mg or by its development code TP-7. In the chemical literature it is described as a tuftsin analogue or by its one-letter sequence TKPRPGP, and its CAS number is 129954-34-3. The acetylated derivative sold separately is N-Acetyl Selank, often shortened to NA-Selank, which is a different compound with its own specifications.

How does Selank work?
Selank modulates several systems rather than activating one receptor. It alters the expression of genes involved in GABAergic neurotransmission, including GABA-A receptor subunits, inhibits the enzymes that degrade enkephalins, increases BDNF expression in the hippocampus and changes serotonin metabolism. The tuftsin core also gives it immunomodulatory activity on interleukin-6 and T helper cytokines. The Pro-Gly-Pro tail slows enzymatic breakdown so the peptide remains active longer than tuftsin itself.

What does the research show about Selank?
Most published work comes from Russian laboratories and rodent models. It reports anxiolytic-like behaviour in elevated plus-maze and open-field tests without sedation, improved memory consolidation in learning tasks, changes in GABA-related gene expression, inhibition of enkephalin-degrading enzymes in serum and effects on interleukin-6 expression. Selank is available as a nasal product in Russian pharmacies, but outside that setting the evidence is preclinical and no Australian regulator has evaluated the compound.

Can I buy Selank at Chemist Warehouse or a pharmacy in Australia?
No. There is no Selank product registered on the Australian Register of Therapeutic Goods, so Chemist Warehouse, Priceline and other retail pharmacies do not stock it. The lyophilised Selank supplied by Omega Peptides Australia is a research-grade chemical intended for laboratory work, which is a different category of product from a medicine dispensed by a pharmacist.

Can Australian compounding pharmacies supply Selank?
Compounding pharmacies in Australia may only prepare a medicine for an individual patient against a valid prescription, and the TGA has published specific guidance warning pharmacists about compounding and supplying unapproved peptide products. Selank is not an approved medicine here, so it is not a routine compounding item. Research suppliers such as Omega Peptides Australia provide the lyophilised research compound, which is a different product intended for in-vitro work rather than for dispensing.

How do you reconstitute Selank?
Allow the vial to reach room temperature, then add bacteriostatic water slowly down the inside wall of the vial rather than directly onto the powder. Swirl gently until the solution is clear; do not shake, because agitation can damage peptide bonds. The volume of diluent depends on the concentration the research design requires, and our reconstitution calculator can assist with that arithmetic. Refrigerate the reconstituted solution at 2–8°C and use it within 28 days.

How should Selank be stored?
Keep the lyophilised powder sealed at 2–8°C for short-term storage or at −20°C for long-term storage, away from light and moisture, and avoid repeated freeze-thaw cycles. Once reconstituted with bacteriostatic water the solution should be kept refrigerated at 2–8°C and used within 28 days. Selank contains no methionine or cysteine, so it is less prone to oxidation than Semax, but the lysine and arginine residues make it hygroscopic and the vial should stay sealed until use.

Where can I buy Selank in Australia?
Selank 10mg is available directly from Omega Peptides Australia. Stock is held domestically, orders placed before 12pm are dispatched the same day, and every batch is supported by an independent Certificate of Analysis you can check before ordering. Selank sits within our broader research peptides collection alongside Semax, N-Acetyl Selank and the other nootropic research compounds we carry.

What does Selank cost in Australia?
Selank is $79.99 for a 10mg vial from Omega Peptides Australia, which works out to about $8.00 per mg. The Semax and Selank Bundle is $169.99 and includes one 10mg vial of each peptide plus 10mL bacteriostatic water, insulin syringes and alcohol swabs, lowering the combined cost compared with purchasing each item individually. All pricing is in Australian dollars, and domestic tracked shipping is calculated at checkout.

How do I get Selank online in Australia?
Open the Selank product page, select the 10mg vial, add it to your cart and complete checkout. Orders are shipped with tracked domestic delivery in discreet, unbranded packaging that gives no indication of the contents. Orders placed before 12pm on a business day are dispatched the same day, and later orders leave on the next business day. Tracking details are emailed as soon as the parcel is lodged with the carrier.

Is Selank legal in Australia?
Omega Peptides Australia supplies Selank strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine or supplement. Purchasers are responsible for ensuring their intended use complies with all applicable laws. This research-only condition applies to every compound in our catalogue and is stated on each product page and on the COA documentation.

Selank vs Semax: what is the difference and why are they paired?
Both are Russian heptapeptides sharing a Pro-Gly-Pro tail, but they come from different parents. Selank is derived from the immune peptide tuftsin and is studied for anxiety, stress and immune endpoints through GABAergic and enkephalin mechanisms. Semax is derived from ACTH(4-10) and is studied for attention, memory and neuroprotection through BDNF and melanocortin pathways. Researchers pair them because their profiles are complementary, and the Semax and Selank Bundle supplies both with lab consumables.

Is Selank available in Australia?
Yes, as a research-grade lyophilised peptide from domestic suppliers. Omega Peptides Australia holds Selank 10mg in Australian stock, COA verified, with same-day dispatch before 12pm.

Can you get Selank in Australia?
Yes, from an Australian research peptide supplier holding domestic stock. Omega Peptides Australia ships Selank from within Australia on tracked delivery with the batch certificate published.

What is the tested purity of Selank?
The current batch (#199776) was tested by Janoshik Analytical on 9 July 2026: 99.34% purity by HPLC with 10.24 mg content per vial. The report can be checked on Janoshik's verification portal using the batch number, and the certificate is published in our COA library.

⚠ For in-vitro research and laboratory use only. Not for human or veterinary use.